NeuroEVs – Marker for Stress and Recovery
Blood test measuring brain-related vesicles for biological insights into stress and recovery.
Leaky Brain? Biological Traces of Stress in the Blood
Prolonged stress not only affects how we feel – it can also leave marks on the body.
New research shows that the brain's support cells, astrocytes, can release small signalling carriers into the blood when under strain. These are called NeuroEVs and they offer insights into how the brain reacts to and recovers from stress.
Stress-related mental health issues, such as burnout syndrome, have long been one of the most common reasons for sick leave in Sweden. Burnout can affect individuals of all ages, with symptoms such as fatigue, impaired concentration, and memory that may persist long after the acute stress has subsided.
To understand what happens in the brain during prolonged stress, objective measures are needed. NeuroEVs thus represent a new approach for studying the brain's response to strain and recovery – a novel tool to be utilized in diagnostics.

Astrocytes communicate with surrounding cells by releasing small extracellular vesicles, known as NeuroEVs. These can provide clues about how the brain is affected by stress and burnout.
What are NeuroEVs?
NeuroEVs are extracellular vesicles released from the brain's cells, primarily astrocytes.
They function as the body's own messengers, capable of transporting biological information between cells.
Research has shown that during prolonged stress, these vesicles can increase in the blood, which reflects changes in brain activity.
Research has demonstrated that levels of NeuroEVs in the blood increase in:
These findings suggest that NeuroEVs could be a promising biological marker for assessing how the brain is affected by chronic stress and the progression of recovery over time.
FBMLab's NeuroEV Analysis
FBMLab has developed and refined methods for measuring brain-related vesicles with high precision.
Supported by scientific publications, we offer the NeuroEV analysis – a tool for tracking individual changes in the brain's stress response over time.
The analysis is based on:
Standardized blood sampling for safe and easy testing
Flow cytometric detection of astrocyte-derived vesicles
Advanced data processing and reporting of individual profiles
How it works
Ordering - You order and pay for the analysis directly through our website
Health Declaration & E-Referral - After payment, you fill out a digital health declaration (approx. 5 minutes). Then, your electronic referral is created, and you can proceed to sample collection immediately.
Sample Collection – You provide a blood sample at a chosen collection site (walk-in).
Analysis & Results - The sample is analyzed in our laboratory, and you receive a detailed report digitally within approximately 10 days.
The report shows your NeuroEV levels and any trends. For a comprehensive overview, follow-up every six months is recommended.
Medical Follow-Up
If your levels are elevated, a medical assessment through our partner NEM Health (Nordic Executive Medicine) is recommended. Contact information is provided in your report.

